Key Terms
14.1
Basic Principles of Pharmacology
pharmacodynamics ,
bioavailability ,
therapeutic window ,
pharmacokinetics ,
enteral ,
parenteral ,
onset of action ,
oral ,
first-pass metabolism ,
intravenous ,
inhalation ,
intranasal ,
transdermal ,
blood-brain barrier ,
lipid-solubility ,
prodrugs ,
drug-drug interactions ,
competitive enzyme inhibition ,
half-life ,
duration of action ,
binding site ,
ligand ,
binding affinity ,
ligand-gated ion channels ,
metabotropic receptors ,
endogenous ligand ,
exogenous ligand ,
dose-response curve ,
full agonist ,
partial agonist ,
constitutive activity ,
inverse agonist ,
antagonist ,
biased agonism ,
allosteric modulator
14.2
Psychotherapeutics
Psychotherapeutics ,
benzodiazepines ,
light-dark choice test ,
major depressive disorder (MDD) ,
anhedonia ,
comorbid ,
selective serotonin reuptake inhibitors ,
first-line medications ,
monoamine hypothesis ,
neurotrophic model ,
brain-derived neurotrophic factor ,
treatment-resistant depression ,
unpredictable chronic mild stress ,
placebo ,
placebo effect ,
psychosis ,
positive symptoms ,
negative symptoms ,
conventional antipsychotics ,
atypical antipsychotics ,
psychostimulants
14.3
Neural Circuitry of Drug Reward
ventral tegmental area ,
mesolimbic pathway ,
mesocortical pathway ,
mesocorticolimbic dopamine pathway ,
nucleus accumbens ,
microdialysis ,
prefrontal cortex ,
hedonia hypothesis ,
reward prediction error hypothesis ,
incentive salience theory ,
stimulants ,
depressants ,
hallucinogens ,
narcotics ,
opiate ,
respiratory depression ,
naloxone ,
binge drinking ,
nicotinic acetylcholine receptor ,
cannabinoid receptor
14.4
Neurobiology of Addiction
substance use disorder ,
tolerance ,
withdrawal ,
chronic relapse ,
dependence ,
intravenous self-administration ,
fixed ratio schedule ,
progressive ratio schedule ,
breakpoint ,
extinction ,
reinstatement ,
genome-wide association studies ,
brain disease model of addiction
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