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14.1 Basic Principles of Pharmacology

1.
________ refers to the physiological and behavioral effects of drugs, whereas ________ refers to the movement of the drug throughout the body.
2 .
An ________ is a ligand that prevents the activation of the receptor by blocking the binding of the agonist.

14.2 Psychotherapeutics

3.
Dopaminergic neurons synthesize the neurotransmitter dopamine and their cell bodies are located in the ________.
4 .
________ activate mu-opioid receptors on GABAergic VTA interneurons, leading to inhibition of GABA neurons and increased dopamine release onto the NAc.

14.3 Neural Circuitry of Drug Reward

5.
The ________ stage of addiction is associated with the euphoric effects of many psychoactive drugs.

14.4 Neurobiology of Addiction

6 .
________ block reuptake of serotonin into presynaptic terminals, leading to increased postsynaptic serotonin signaling.